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  • Prime rate 6.75% flat
  • Fed funds 3.63% flat
  • SOFR 3.64% up0.02
  • Treasury 1Y 4.15% up0.16
  • Treasury 10Y 4.71% up0.14
Updated: EST

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Latest Funding Benchmarks

Updated: EST

The table lists each benchmark, its current value, and its change over 7 days.

Latest Funding Benchmarks
Benchmark Rate 7 days
Bank prime loan rate DPRIME · Common base rate for pricing many variable-rate business loans and credit lines. Source observation dated July 22, 2026. Retrieved July 25, 2026 7:37 pm. Source vintage July 23, 2026. 6.75% flat
Effective federal funds rate DFF · Overnight interbank rate published by the Federal Reserve Bank of New York. Source observation dated July 23, 2026. Retrieved July 25, 2026 7:37 pm. Source vintage July 24, 2026. 3.63% flat
Secured Overnight Financing Rate SOFR · Broad overnight financing benchmark based on U.S. Treasury repurchase transactions. Source observation dated July 23, 2026. Retrieved July 25, 2026 7:38 pm. Source vintage July 24, 2026. 3.64% up0.02
1-year Treasury yield DGS1 · One-year U.S. Treasury constant maturity market yield. Source observation dated July 23, 2026. Retrieved July 25, 2026 7:38 pm. Source vintage July 24, 2026. 4.15% up0.16
10-year Treasury yield DGS10 · Ten-year U.S. Treasury constant maturity market yield. Source observation dated July 23, 2026. Retrieved July 25, 2026 7:38 pm. Source vintage July 24, 2026. 4.71% up0.14

FRED rows are economic benchmarks. Product rows appear only from an approved, sourced methodology and are not lender offers.

Benchmark source: FRED®, Federal Reserve Bank of St. Louis (opens in a new tab)

Verified Funding Partners

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Open Grant Opportunities

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Applications open

Rigorous Impact Evaluation of Programs to Prevent Teen Pregnancy and Achieve Optimal Health

Funding
$650,000–$1,250,000
Deadline
July 23, 2026
Geography
National

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2026 grants under the authority of Division B, Title II of the Consolidated Appropriations Act, 2026 (Public Law 119-75).This notice solicits applications for projects to rigorously evaluate promising interventions that contribute to adolescent optimal health and preventing teen pregnancy,…

Eligibility details

The Office of Population Affairs (OPA) announces the anticipated availability of funds for Fiscal Year (FY) 2026 grants under the authority of Division B, Title II of the Consolidated Appropriations Act, 2026 (Public Law 119-75).This notice solicits applications for projects to rigorously evaluate promising interventions that contribute to adolescent optimal health and preventing teen pregnancy, sexually transmitted infections (STIs), behavioral risk factors underlying teen pregnancy,…

Applications open

DoW Melanoma Research Program Survivorship Research Award

Funding
Up to $2,040,000
Deadline
October 14, 2026
Geography
National

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Survivorship Research Award addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families and/or their care partners in the…

Eligibility details

Summary: The fiscal year 2026 (FY26) Melanoma Research Program (MRP) Survivorship Research Award addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families and/or their care partners in the near term. Proposed studies focusing exclusively on animal models or…

Applications open

Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)

Deadline
May 7, 2028
Geography
National

This Notice of Funding Opportunity (NOFO) will support students at institutions without NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g.…

Eligibility details

This Notice of Funding Opportunity (NOFO) will support students at institutions without NIH-funded institutional predoctoral dual-degree training programs. The purpose of the Kirschstein-NRSA, dual-doctoral degree, predoctoral fellowship (F30) is to enhance the integrated research and clinical training of promising predoctoral students, who are matriculated in a combined MD/PhD or other dual-doctoral degree training program (e.g. DO/PhD, DDS/PhD, AuD/PhD, DVM/PhD), and who intend careers as...

Applications open

Certified Community Behavioral Health Clinic (CCBHC) Improvement and Advancement Grant

Funding
Up to $1,000,000
Deadline
August 17, 2026
Geography
National

The purpose of this program is to sustain and enhance services at existing Certified Community Behavioral Health Clinics (CCBHCs). This includes serving individuals across the lifespan with or at risk for mental health and/or substance use disorders (SUDs). CCBHCs are community-based clinics that offer coordinated, evidence-based outpatient services, including crisis services, while also enhancing access…

Eligibility details

The purpose of this program is to sustain and enhance services at existing Certified Community Behavioral Health Clinics (CCBHCs). This includes serving individuals across the lifespan with or at risk for mental health and/or substance use disorders (SUDs). CCBHCs are community-based clinics that offer coordinated, evidence-based outpatient services, including crisis services, while also enhancing access for anyone in need and coordinating care to mitigate gaps…

Applications open

Critical Minerals and Materials Accelerator Notice of Funding Opportunity

Funding
$1–$3,000,000
Deadline
July 23, 2026
Geography
National

Modification 0002 Annoucement (04/21/26): Extended LOI due date to 4/24/2026 Extended TA1 due date to 5/29/2026 Extended TA2 due date to 6/25/2026 Extended TA3 due date to 7/23/2026 Modification 0001 Announcement (04/15/26): Corrected units in Figure 3; Replaced instances of ‘FOA’ with ‘NOFO’ in Section D. Expected Performance Goals, Application Metrics; Corrected LOI character limit…

Eligibility details

Modification 0002 Annoucement (04/21/26): Extended LOI due date to 4/24/2026 Extended TA1 due date to 5/29/2026 Extended TA2 due date to 6/25/2026 Extended TA3 due date to 7/23/2026 Modification 0001 Announcement (04/15/26): Corrected units in Figure 3; Replaced instances of ‘FOA’ with ‘NOFO’ in Section D. Expected Performance Goals, Application Metrics; Corrected LOI character limit in Section IV.C. This Notice of Funding Opportunity (NOFO) supports…

Applications open

Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

Deadline
November 2, 2028
Geography
National

This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct investigator-initiated single site clinical trials including efficacy, comparative effectiveness, pragmatic and/or dissemination and implementation science clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, dissemination and…

Eligibility details

This Notice of Funding Opportunity (NOFO) supports applications to develop and conduct investigator-initiated single site clinical trials including efficacy, comparative effectiveness, pragmatic and/or dissemination and implementation science clinical trials. Trials using innovative designs such as platform trials, adaptive, and Bayesian designs are encouraged. These trials may include ones that test different therapeutic, behavioral, dissemination and implementation science clinical trials...

Applications open

Division of Chemistry: Disciplinary Research Programs

Funding
Up to $105,000,000
Deadline
September 30, 2026
Geography
National

This solicitation applies to six (of the nine) CHE Disciplinary Research Programs: Chemical Catalysis (CAT); Chemical Measurement and Imaging (CMI); Chemical Mechanism, Function and Properties (CMFP); Chemical Synthesis (SYN); Environmental Chemical Sciences (ECS); and Macromolecular, Supramolecular and Nanochemistry (MSN). All proposals submitted to these six CHE Disciplinary Research Programs (other than the following exceptions) must…

Eligibility details

This solicitation applies to six (of the nine) CHE Disciplinary Research Programs: Chemical Catalysis (CAT); Chemical Measurement and Imaging (CMI); Chemical Mechanism, Function and Properties (CMFP); Chemical Synthesis (SYN); Environmental Chemical Sciences (ECS); and Macromolecular, Supramolecular and Nanochemistry (MSN). All proposals submitted to these six CHE Disciplinary Research Programs (other than the following exceptions) must be submitted through this solicitation, otherwise they...

Applications open

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

Deadline
January 7, 2027
Geography
National

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation…

Eligibility details

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the…

Applications open

Cybersecurity Innovation for Cyberinfrastructure

Funding
Up to $1,200,000
Deadline
January 20, 2027
Geography
National

The objective of the Cybersecurity Innovation for Cyberinfrastructure (CICI) program is to advance scientific discovery and innovation by enhancing the security and privacy of cyberinfrastructure. CICI supports efforts to develop, deploy and integrate cybersecurity that will benefit the broader scientific community by securing science data, computation, collaborations workflows, and infrastructure. CICI recognizes the unique nature…

Eligibility details

The objective of the Cybersecurity Innovation for Cyberinfrastructure (CICI) program is to advance scientific discovery and innovation by enhancing the security and privacy of cyberinfrastructure. CICI supports efforts to develop, deploy and integrate cybersecurity that will benefit the broader scientific community by securing science data, computation, collaborations workflows, and infrastructure. CICI recognizes the unique nature of modern, complex, data-driven, distributed, rapid, and...

Applications open

Boosting Innovative GEOINT – Science & Technology Broad Agency Announcement (BIG-ST BAA)

Deadline
December 14, 2026
Geography
National

The Boosting Innovative GEOINT-Science and Technology (BIG-ST) Broad Agency Announcement (BAA) invites proposers to submit innovative concepts to address hard GEOINT problems that align to one or more of the following technical domains: (1) Foundational GEOINT, (2) Advanced Phenomenologies, and (3) Analytic Technologies. BAA Process and Topic Call Publication: The BIG-ST BAA is a general…

Eligibility details

The Boosting Innovative GEOINT-Science and Technology (BIG-ST) Broad Agency Announcement (BAA) invites proposers to submit innovative concepts to address hard GEOINT problems that align to one or more of the following technical domains: (1) Foundational GEOINT, (2) Advanced Phenomenologies, and (3) Analytic Technologies. BAA Process and Topic Call Publication: The BIG-ST BAA is a general announcement of NGA’s research interest, including criteria for selecting proposals…

Applications open

U.S. Embassy to the United Kingdom Public Diplomacy Section Annual Program Statement

Funding
$20,000–$100,000
Deadline
August 10, 2026
Geography
National

The U.S. Embassy to the United Kingdom of the U.S. Department of State is pleased to announce that funding is available through its Public Diplomacy Section program. This is an Annual Program Statement, outlining our funding priorities, the strategic themes we focus on, and the procedures for submitting requests for funding. Please refer to the…

Eligibility details

The U.S. Embassy to the United Kingdom of the U.S. Department of State is pleased to announce that funding is available through its Public Diplomacy Section program. This is an Annual Program Statement, outlining our funding priorities, the strategic themes we focus on, and the procedures for submitting requests for funding. Please refer to the full NOFO document for a full outline of the program.

Applications open

FY 2026 Community Solutions Program

Funding
$3,000,000–$3,000,000
Deadline
July 23, 2026
Geography
National

The Global Leaders Division in the Office of Citizen Exchanges at the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA) seeks proposals for a cooperative agreement to design and implement the FY 2026 Community Solutions Program (CSP). The United States has a strong tradition of hard work, entrepreneurship, and local leadership that…

Eligibility details

The Global Leaders Division in the Office of Citizen Exchanges at the U.S. Department of State’s Bureau of Educational and Cultural Affairs (ECA) seeks proposals for a cooperative agreement to design and implement the FY 2026 Community Solutions Program (CSP). The United States has a strong tradition of hard work, entrepreneurship, and local leadership that has powered economic growth. American communities succeed by building on…

Applications open

Foster Parents Network Analytics Hub (HUB)

Funding
$1,500,000–$2,500,000
Deadline
August 10, 2026
Geography
National

To support the Administration for Children and Families" initiative, A Home for Every Child, the Children"s Bureau will award one grant to establish the Foster Parents Network Analytics Hub (HUB) to achieve a foster home-to-child ratio of more than 1:1 in every state by 2029. The HUB will advance the goal by providing states with…

Eligibility details

To support the Administration for Children and Families" initiative, A Home for Every Child, the Children"s Bureau will award one grant to establish the Foster Parents Network Analytics Hub (HUB) to achieve a foster home-to-child ratio of more than 1:1 in every state by 2029. The HUB will advance the goal by providing states with advanced analytics tools and intensive technical assistance to optimize their…

Applications open

F26AS00051_FY 2026 Competitive State Wildlife Grant (C-SWG) Program_Funding Opportunity Announcement

Funding
$50,000–$1,000,000
Deadline
September 18, 2026
Geography
National

The Competitive State Wildlife Grant (C-SWG) Program provides Federal cost-sharing awards that help the State, Territory, and District of Columbia fish and wildlife agencies and their regional associations design and implement proactive conservation programs benefiting wildlife and their habitats. Proactive approaches to conservation help these recipients and their conservation partners avoid more prescriptive Federal regulatory…

Eligibility details

The Competitive State Wildlife Grant (C-SWG) Program provides Federal cost-sharing awards that help the State, Territory, and District of Columbia fish and wildlife agencies and their regional associations design and implement proactive conservation programs benefiting wildlife and their habitats. Proactive approaches to conservation help these recipients and their conservation partners avoid more prescriptive Federal regulatory requirements associated with species listing under the Endangered...

Applications open

NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

Deadline
January 7, 2027
Geography
National

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is…

Eligibility details

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore,…

Applications open

FY2026 Support for 988 Tribal Response Cooperative Agreements

Funding
Up to $1,500,000
Deadline
July 17, 2026
Geography
National

The purpose of the 988 Tribal response program is to improve connection and response to 988 contacts (including calls, chats, and texts) originating in Tribal communities and/or activated by American Indians/Alaska Natives. American Indian and Alaska Native communities experience a significantly higher suicide risk compared to the general population. CDC reports that in 2022 non-Hispanic…

Eligibility details

The purpose of the 988 Tribal response program is to improve connection and response to 988 contacts (including calls, chats, and texts) originating in Tribal communities and/or activated by American Indians/Alaska Natives. American Indian and Alaska Native communities experience a significantly higher suicide risk compared to the general population. CDC reports that in 2022 non-Hispanic Al/AN people had a suicide rate 91% greater than the…

Applications open

FY 2026 DRUG COURT TRAINING AND TECHNICAL ASSISTANCE COMPETITIVE COOPERATIVE AGREEMENT SOLICITATION

Funding
$6,000,000–$6,000,000
Deadline
August 27, 2026
Geography
National

ONDCP’s Drug Court Training and Technical Assistance Cooperative Agreement supports training and technical assistance (TTA) to ensure access to evidence-based addiction treatment through drug courts, including when substance use disorder co-occurs with other mental healthconditions. ONDCP seeks to reduce drug use and its consequences through evidence-based treatment that leads to long-term recovery, and this cooperative…

Eligibility details

ONDCP’s Drug Court Training and Technical Assistance Cooperative Agreement supports training and technical assistance (TTA) to ensure access to evidence-based addiction treatment through drug courts, including when substance use disorder co-occurs with other mental healthconditions. ONDCP seeks to reduce drug use and its consequences through evidence-based treatment that leads to long-term recovery, and this cooperative agreement will support the President’s priorities by applying this to…

Applications open

Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)

Funding
Up to $250,000
Deadline
January 7, 2027
Geography
National

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science approaches that can help individuals understand and improve their health through actionable insights. NLM seeks applications that further the science of personal health informatics by providing meaningful and actionable insights to individuals through innovative personal…

Eligibility details

The purpose of this Notice of Funding Opportunity (NOFO) is to advance the development of novel informatics and data science approaches that can help individuals understand and improve their health through actionable insights. NLM seeks applications that further the science of personal health informatics by providing meaningful and actionable insights to individuals through innovative personal health data collection, integration, analysis, and personalized risk assessments and…

Applications open

Social disconnection and Suicide Risk in Late Life (R01 Clinical Trial Optional)

Deadline
September 7, 2026
Geography
National

This initiative seeks to solicit applications for research projects that address the link between social disconnection including both objective social isolation as well as perceived social isolation (otherwise known as loneliness) and suicide in late-life. Emphasis is placed on research that identifies neurobiological and environmental mechanisms associated with social isolation and loneliness that increase risk…

Eligibility details

This initiative seeks to solicit applications for research projects that address the link between social disconnection including both objective social isolation as well as perceived social isolation (otherwise known as loneliness) and suicide in late-life. Emphasis is placed on research that identifies neurobiological and environmental mechanisms associated with social isolation and loneliness that increase risk for suicidal thoughts and behavior in late-life, that uses an…

Applications open

Research Experiences for Undergraduates

Funding
$5,000–$500,000
Deadline
August 19, 2026
Geography
National

The Research Experiences for Undergraduates (REU) program supports active research participation by undergraduate students in any of the areas of research funded by the National Science Foundation. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. This solicitation features two mechanisms for supporting…

Eligibility details

The Research Experiences for Undergraduates (REU) program supports active research participation by undergraduate students in any of the areas of research funded by the National Science Foundation. REU projects involve students in meaningful ways in ongoing research programs or in research projects specifically designed for the REU program. This solicitation features two mechanisms for supporting student research: REU Sites are based on independent proposals to…

Applications open

Amyotrophic Lateral Sclerosis (ALS) Intermediate Patient Population Expanded Access (U01 Clinical Trial Required)

Funding
Up to $40,000,000
Deadline
November 10, 2026
Geography
National

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the conduct of scientific research utilizing data from expanded access (EA) for investigational drugs or biological products as described in section 561 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 360bbb). These applications will target intermediate size populations of…

Eligibility details

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for the conduct of scientific research utilizing data from expanded access (EA) for investigational drugs or biological products as described in section 561 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. 360bbb). These applications will target intermediate size populations of patients living with amyotrophic lateral sclerosis (ALS) who are not…

Applications open

Fiscal Year 2026 Intercity Passenger Rail Program

Funding
Up to $9,500,000
Deadline
July 24, 2026
Geography
National

The Fiscal Year (FY) 2026 Intercity Passenger Rail (IPR) – Amtrak program is one of four grant programs that constitute DHS/FEMA’s focus on transportation infrastructure security activities. These grant programs are part of a comprehensive set of measures authorized by Congress and implemented by DHS to help strengthen the Nation’s critical infrastructure against potential terrorist…

Eligibility details

The Fiscal Year (FY) 2026 Intercity Passenger Rail (IPR) – Amtrak program is one of four grant programs that constitute DHS/FEMA’s focus on transportation infrastructure security activities. These grant programs are part of a comprehensive set of measures authorized by Congress and implemented by DHS to help strengthen the Nation’s critical infrastructure against potential terrorist attacks. The IPR provides funds to Amtrak to protect critical…

Applications open

Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)

Deadline
May 7, 2027
Geography
National

Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign...

Eligibility details

Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign...

Applications open

Preventing Youth Overdose: Treatment, Recovery, Education, Awareness and Training

Funding
Up to $450,000
Deadline
July 16, 2026
Geography
National

The purpose of this program is to improve local awareness among youth and young adults of the risks associated with fentanyl and provide youth and young adults with opioid use disorder and other substance use disorder prevention, treatment and recovery support services.

Eligibility details

The purpose of this program is to improve local awareness among youth and young adults of the risks associated with fentanyl and provide youth and young adults with opioid use disorder and other substance use disorder prevention, treatment and recovery support services.

Applications open

DoW Neurofibromatosis Research Academy – Scholar Award

Funding
Up to $3,600,000
Deadline
September 22, 2026
Geography
National

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Neurofibromatosis Research Academy – Scholar Award (NFRA-SA) supports early-career independent investigators (Scholars) joining the Neurofibromatosis Research Academy to pursue a neurofibromatosis project that may include basic, translational, and/or clinical research. The proposed research should address at least one of the FY26 NFRP Areas of Emphasis,…

Eligibility details

Summary: The fiscal year 2026 (FY26) Neurofibromatosis Research Program (NFRP) Neurofibromatosis Research Academy – Scholar Award (NFRA-SA) supports early-career independent investigators (Scholars) joining the Neurofibromatosis Research Academy to pursue a neurofibromatosis project that may include basic, translational, and/or clinical research. The proposed research should address at least one of the FY26 NFRP Areas of Emphasis, under the leadership of the NFRA Director and Deputy Director....

Applications open

DoW Kidney Cancer, Academy of Kidney Cancer Investigators – Early-Career Scholar Award

Funding
Up to $2,400,000
Deadline
September 28, 2026
Geography
National

Summary: Initially created in fiscal year 2019 (FY19), the Kidney Cancer Research Program (KCRP) Academy of Kidney Cancer Investigators (AKCI) is a unique interactive virtual academy providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty. The Academy pairs Early Career Scholars (ECS) with established investigators (Designated Mentors) under the oversight of…

Eligibility details

Summary: Initially created in fiscal year 2019 (FY19), the Kidney Cancer Research Program (KCRP) Academy of Kidney Cancer Investigators (AKCI) is a unique interactive virtual academy providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty. The Academy pairs Early Career Scholars (ECS) with established investigators (Designated Mentors) under the oversight of the AKCI Leadership Team, a Designated Mentor Panel, and the…

Applications open

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

Funding
Up to $750,000
Deadline
October 20, 2027
Geography
National

This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this FOA is to promote a significant improvement in the translational relevance of animal models or ex vivo systems…

Eligibility details

This funding opportunity announcement (FOA) encourages the development and validation of animal models and human/animal tissue ex vivo systems that recapitulate the phenotypic and physiologic characteristics of a defined neurological or neuromuscular disorder. The goal of this FOA is to promote a significant improvement in the translational relevance of animal models or ex vivo systems that will be utilized to facilitate future development of neurotherapeutics.…

Applications open

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

Funding
Up to $250,000
Deadline
April 15, 2027
Geography
National

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from…

Eligibility details

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.

Applications open

DoW Rare Cancers Resource and Community Development Award

Funding
Up to $5,600,000
Deadline
November 18, 2026
Geography
National

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Resource and Community Development Award (RCDA) supports the development of research resources and clinical or preclinical datasets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Research supporting this funding opportunity should fill one of…

Eligibility details

Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Resource and Community Development Award (RCDA) supports the development of research resources and clinical or preclinical datasets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Research supporting this funding opportunity should fill one of the following major gaps: Lack of research and clinical resources,…

Applications open

Focused Technology Research and Development (R01 Clinical Trial Not Allowed)

Deadline
January 7, 2028
Geography
National

This Notice of Funding Opportunity (NOFO) supports projects relevant to the NIGMS mission that focus solely on the development of technologies with potential to enable acquisition of biomedical knowledge. Projects should be justified in terms of technical innovation and utility of such technical innovation for impacting future biomedical research. Outcomes or products of the proposed…

Eligibility details

This Notice of Funding Opportunity (NOFO) supports projects relevant to the NIGMS mission that focus solely on the development of technologies with potential to enable acquisition of biomedical knowledge. Projects should be justified in terms of technical innovation and utility of such technical innovation for impacting future biomedical research. Outcomes or products of the proposed project should significantly advance the current state of the art…

Applications open

Fair Housing Initiatives Program – Fair Housing Organizations Initiative FY2025 and FY2026

Funding
$1,700,000–$8,900,000
Deadline
August 6, 2026
Geography
National

The program funds organizations to build capacity to engage in fair housing enforcement activities and fair housing enforcement related activities, and engage in such activities for the purpose of supporting the continued development or implementation of initiatives which enforce the rights granted under the Fair Housing Act, particularly in those areas of the country which…

Eligibility details

The program funds organizations to build capacity to engage in fair housing enforcement activities and fair housing enforcement related activities, and engage in such activities for the purpose of supporting the continued development or implementation of initiatives which enforce the rights granted under the Fair Housing Act, particularly in those areas of the country which are currently underserved by fair housing enforcement organizations as well…

Applications open

DoW, Ovarian Cancer, Pilot Award

Funding
Up to $4,550,000
Deadline
October 1, 2026
Geography
National

Summary: The Ovarian Cancer Pilot Award supports research that expands or modifies current thinking about and/or approaches in ovarian cancer, exploring innovative concepts or theories in ovarian cancer that could ultimately lead to critical discoveries or major advancements that will drive the field forward. Distinctive Features: Innovation is key. Research projects that demonstrate exceptional scientific…

Eligibility details

Summary: The Ovarian Cancer Pilot Award supports research that expands or modifies current thinking about and/or approaches in ovarian cancer, exploring innovative concepts or theories in ovarian cancer that could ultimately lead to critical discoveries or major advancements that will drive the field forward. Distinctive Features: Innovation is key. Research projects that demonstrate exceptional scientific merit but lack innovation do not meet the intent of…

Applications open

AI Accelerator Grant

Funding
Up to $1,000,000
Deadline
September 10, 2026
Geography
National

The AI Accelerator Grant, provided by the Global Ovarian Cancer Research Consortium (comprising OCRA, Ovarian Cancer Action, Ovarian Cancer Canada, and The Ovarian Cancer Research Foundation), awards $1 million USD plus AWS compute support to international, multidisciplinary research teams using artificial intelligence to improve ovarian cancer survival rates. Introduced in 2025 in partnership with Microsoft's…

Eligibility details

The AI Accelerator Grant, provided by the Global Ovarian Cancer Research Consortium (comprising OCRA, Ovarian Cancer Action, Ovarian Cancer Canada, and The Ovarian Cancer Research Foundation), awards $1 million USD plus AWS compute support to international, multidisciplinary research teams using artificial intelligence to improve ovarian cancer survival rates. Introduced in 2025 in partnership with Microsoft's AI for Good Lab, the grant supports projects with lead…

Applications open

NIH Research Education Program – Research Experiences (Parent R25 – Clinical Trial Not Allowed)

Deadline
May 5, 2029
Geography
National

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty…

Eligibility details

The National Institutes of Health (NIH) Research Education Program supports research education activities in the mission areas of the NIH. The overarching goal of the Research Education program is to:Support educational activities that complement and/or enhance training of a workforce to meet the nation's biomedical, behavioral and clinical research needs;Help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and…

Applications open

Entergy Charitable Foundation Grants

Deadline
August 1, 2026
Geography
National

The Entergy Charitable Foundation provides grants to nonprofit organizations to support initiatives that help create and sustain thriving communities. The foundation focuses funding on three areas: education and workforce development, poverty solutions, and environmental programs. Eligible applicants must be 501(c)(3) tax-exempt organizations, schools, hospitals, governmental units, religious institutions, war-veterans organizations, volunteer fire departments, or state/local…

Eligibility details

The Entergy Charitable Foundation provides grants to nonprofit organizations to support initiatives that help create and sustain thriving communities. The foundation focuses funding on three areas: education and workforce development, poverty solutions, and environmental programs. Eligible applicants must be 501(c)(3) tax-exempt organizations, schools, hospitals, governmental units, religious institutions, war-veterans organizations, volunteer fire departments, or state/local governments making...

Applications open

DoW Lupus, Transformative Vision Development Award

Funding
Up to $500,000
Deadline
August 24, 2026
Geography
National

Summary: This funding mechanism supports planning and development activities and pilot studies that will generate preliminary data and demonstrate feasibility for achieving the aims of a future interventional study. Successful studies may be submitted to a future Lupus Research Program (LRP) Transformative Vision Award (TVA), or equivalent, for funding consideration (See Funding Opportunity Number HT942526LRPTVA…

Eligibility details

Summary: This funding mechanism supports planning and development activities and pilot studies that will generate preliminary data and demonstrate feasibility for achieving the aims of a future interventional study. Successful studies may be submitted to a future Lupus Research Program (LRP) Transformative Vision Award (TVA), or equivalent, for funding consideration (See Funding Opportunity Number HT942526LRPTVA for additional information). Research must address at least one of…

Applications open

DoW Pancreatic Cancer Research Program, Translational Research Partnership Award

Funding
Up to $6,600,000
Deadline
October 7, 2026
Geography
National

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or…

Eligibility details

Summary: The fiscal year 2026 (FY26) Pancreatic Cancer Research Program (PCARP) Translational Research Partnership Award supports partnerships between clinicians, population scientists, applied scientists and/or basic scientists that will accelerate the movement of promising ideas in pancreatic cancer toward clinical applications. The partnership must include at least one member with expertise in pancreatic cancer research or pancreatic cancer patient care. All applications must address at...

Applications open

RFA-IP-18-000

Deadline
September 30, 2030
Geography
National

Submit application as necessary for Type 6 Applications.

Eligibility details

Submit application as necessary for Type 6 Applications.

Applications open

DoW Reconstructive Transplant, Concept Award

Funding
Up to $600,000
Deadline
September 16, 2026
Geography
National

Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Concept Award supports the exploration of highly innovative new concepts or untested theories that address an important problem relevant to reconstructive transplantation. The Concept Award does not support clinical trials . Distinctive Features: ·         Innovation: Innovative research may introduce a new paradigm, challenge existing…

Eligibility details

Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Concept Award supports the exploration of highly innovative new concepts or untested theories that address an important problem relevant to reconstructive transplantation. The Concept Award does not support clinical trials . Distinctive Features: ·         Innovation: Innovative research may introduce a new paradigm, challenge existing paradigms, examine existing...

Applications open

Advancing Research on Empirically-Supported Interventions for Older Adults Living with Serious Mental Illness (SMI) (R01 Clinical Trial Optional)

Funding
Up to $3,000,000
Deadline
October 15, 2026
Geography
National

The purpose of this notice of funding opportunity (NOFO) is to foster research that will inform and support the optimization, delivery, sustainability, and effectiveness of empirically-supported practices for addressing the mental health needs of older adults with serious mental illness (SMI). To this end, NIMH seeks applications that propose work that is focused on practice-relevant…

Eligibility details

The purpose of this notice of funding opportunity (NOFO) is to foster research that will inform and support the optimization, delivery, sustainability, and effectiveness of empirically-supported practices for addressing the mental health needs of older adults with serious mental illness (SMI). To this end, NIMH seeks applications that propose work that is focused on practice-relevant questions and conducted within and/or across settings where older adults…

Applications open

Limited Competition: National Primate Research Centers (P51) (Clinical Trials Not Allowed)

Deadline
September 25, 2026
Geography
National

This funding opportunity announcement (FOA) encourages grant applications that support the activities of the National Primate Research Centers (NPRCs). Nonhuman primates (NHPs) are most closely related to humans, both physiologically and genetically. Therefore, NHPs are critical animal models for basic and translational research aimed at understanding human biology, both in normal and diseased states. Proper…

Eligibility details

This funding opportunity announcement (FOA) encourages grant applications that support the activities of the National Primate Research Centers (NPRCs). Nonhuman primates (NHPs) are most closely related to humans, both physiologically and genetically. Therefore, NHPs are critical animal models for basic and translational research aimed at understanding human biology, both in normal and diseased states. Proper husbandry and management of NHPs require specialized physical and intellectual...

Applications open

GlobalX Challenge 26.2: Naval Southern Hemisphere Space Weather and Plasmas (NSHSWP)

Funding
Up to $500,000
Deadline
August 31, 2026
Geography
National

This purpose of the GlobalX Challenge is to accelerate the traditional knowledge generation cycle, proving or disproving an applied research theory on an advanced timeline, leading to the discovery of revolutionary dual-use capability for the benefit of the U.S. Navy and Marine Corps, the commercial marketplace, and the public. The expected outcomes of this Challenge…

Eligibility details

This purpose of the GlobalX Challenge is to accelerate the traditional knowledge generation cycle, proving or disproving an applied research theory on an advanced timeline, leading to the discovery of revolutionary dual-use capability for the benefit of the U.S. Navy and Marine Corps, the commercial marketplace, and the public. The expected outcomes of this Challenge are promising, potentially game-changing, applied concepts whose maturity may be…

Applications open

Screening & Treatment for Maternal Mental Health and Substance Use Disorders (MMHSUD)

Funding
Up to $500,000
Deadline
July 17, 2026
Geography
National

The MMHSUD Program helps improve maternal mental health and substance use disorder outcomes for pregnant and postpartum women by providing obstetric, primary care, and other maternal health providers with timely access to teleconsultation, training, and care coordination support including resource and referrals.

Eligibility details

The MMHSUD Program helps improve maternal mental health and substance use disorder outcomes for pregnant and postpartum women by providing obstetric, primary care, and other maternal health providers with timely access to teleconsultation, training, and care coordination support including resource and referrals.

Applications open

Cochran Fellowship Program FY2026

Funding
Up to $150,000
Deadline
August 14, 2026
Geography
National

The U.S. Department of Agriculture, Foreign Agricultural Service, Fellowship Programs, announces this funding opportunity to support the Cochran Fellowship Program by issuing a new award. This opportunity is available to State cooperative institutions or other colleges and universities in the United States, as defined at 7 U.S.C. § 3103. This program is intended to support…

Eligibility details

The U.S. Department of Agriculture, Foreign Agricultural Service, Fellowship Programs, announces this funding opportunity to support the Cochran Fellowship Program by issuing a new award. This opportunity is available to State cooperative institutions or other colleges and universities in the United States, as defined at 7 U.S.C. § 3103. This program is intended to support applied research, extension, and education collaborations between U.S. researchers and…

Applications open

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

Funding
Up to $1,050,000
Deadline
November 13, 2026
Geography
National

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g.,…

Eligibility details

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have...

Applications open

Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

Deadline
May 7, 2027
Geography
National

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related…

Eligibility details

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental…

Applications open

2027 Quality Samples Program

Funding
Up to $2,500,000
Deadline
August 14, 2026
Geography
National

The QSP is designed to encourage the development and expansion of export markets for U.S. agricultural commodities by assisting U.S. entities in providing commodity samples to potential foreign importers to promote a better understanding and appreciation for the high quality of U.S. agricultural commodities.

Eligibility details

The QSP is designed to encourage the development and expansion of export markets for U.S. agricultural commodities by assisting U.S. entities in providing commodity samples to potential foreign importers to promote a better understanding and appreciation for the high quality of U.S. agricultural commodities.

Applications open

Fiscal Year 2026 Port Security Grant Program

Funding
Up to $95,000,000
Deadline
July 24, 2026
Geography
National

Discretionary

Eligibility details

Eligible applicants: County governments; City or township governments; Special district governments; Native American tribal governments (Federally recognized); For profit organizations other than small businesses Discretionary

Applications open

Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (RC2 Clinical Trials Optional)

Deadline
September 28, 2026
Geography
National

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs (PAR-24-272). Successful programs…

Eligibility details

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded UM1 Clinical and Translational Science Awards (CTSA) Program Hubs (PAR-24-272). Successful programs supported through this funding opportunity are expected to lay a…

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Table-Top Free Space Measuring System – USDA-ARS Auburn AL

Response deadline
December 22, 2026
Location
National

This is a Sources Sought notice Only. This is NOT a solicitation for proposals, proposal abstracts, or quotations. This Sources Sought is issued for information and planning purposes only as part of USDA ARS market research and does not itself constitute an RFQ. This requirement is covered under NAICS code 334516 � Ana…

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SBA 7(a) Q1 2026 rate update — prime + 2.75% for loans over $50K

The SBA has released updated base rates for Q1 2026. Most 7(a) loans now carry a ceiling of prime + 2.75% for loans exceeding $50,000 with maturities over 7 years.
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Rural small businesses may apply for grants up to $500,000 for technical assistance, training, and working capital. New 2026 cycle opened February 1.
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Equipment financing
Equipment financing

How to finance equipment in 2026 without hurting cash flow

The right structure makes all the difference. Here’s what commercial banking experts recommend for equipment loans this year.
JR James Rourke
VP Commercial Lending · 5 min read
SBA programs
SBA programs

SBA 504 vs 7(a): which loan is right for your business in 2026?

A side-by-side breakdown of the two most popular SBA programs, who qualifies, and how 2026 rates compare.
ML Maria Lopes
SBA Lending Specialist · 7 min read
Business growth
Business growth

5 funding strategies for small businesses in a 2026 rate environment

Savvy business owners in 2026 are using a mix of instruments to minimize their cost of capital.
TC Thomas Chen
Alt. Lending Strategist · 6 min read
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